FOR IMMEDIATE RELEASE [Covington, KY—June 13, 2022
Bexion Pharmaceuticals, Inc., a mid-stage clinical biopharmaceutical company, announced today that two abstracts submitted for an in-person session at the IPSNO annual meeting to be held in Hamburg, Germany, June 12-15, 2022 has been chosen for poster presentation.
ISPNO is the largest international scientific meeting of multidisciplinary professionals in research, diagnosis, treatment, and rehabilitation of children and adolescents with tumors of the Central Nervous System. The program will include the most recent cutting-edge preclinical and clinical research from the fields of neurosurgery, neuroradiology, neuropathology, biology, radiotherapy, pediatric neuro-oncology, immunotherapy, late effects, rehabilitation, and nursing. ISPNO will also have state-of-the art symposia, interdisciplinary sessions and round tables on the most challenging and timely topics in the field of pediatric neuro-oncology.
Title of the Abstract-Poster Presentations:
A Phase 1, Safety and Dose Escalation Study of BXQ-350 in Combination with Radiation in Pediatric Patients with Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma
A Phase 1, Safety and Dose Escalation Study of BXQ-350 in Patients with Advanced Solid Malignancies Demonstrates that BXQ-350 is Well Tolerated and Shows Signs of Potential Clinical Activity in Ependymoma Patients
Poster Presentation Session:
Monday, June 13th, 2022 from 6:00 – 7:30 pm Central European Summer Time (CEST)
Tuesday, June 14th, 2022 from 5:30 – 7:00 pm Central European Summer Time (CEST)
Gilles Tapolsky, Ph.D., M.B.A., Vice President, Pharmacology at Bexion will be discussing the key findings from these poster presentations.
About Bexion Pharmaceuticals
Bexion Pharmaceuticals, a mid-stage clinical stage biopharmaceutical company, is developing a new generation of biologic immunotherapy to treat solid tumor cancers and Chemotherapy Induced Peripheral Neuropathy (CIPN) with potential portfolio expansion opportunities in other cancers and broader neuropathic pain indications. Bexion’s lead drug candidate is BXQ-350, a first-in-class biologic containing the multifunctional, lysosomal activator protein, Saposin C and a-phosphatidylserine. BXQ-350, an “S1P Activator”, has demonstrated pre-clinical antitumor effects in vitro and in vivo, particularly in colorectal, brain and other solid tumors. Bexion has completed two single agent Phase 1 programs in adults and in a pediatric population. The Phase 1 programs demonstrated a strong safety profile with evidence of single agent activity across a range of solid tumors including Glioblastoma Multiforme (GBM), colorectal cancer and appendiceal cancer. Additionally, other clinical and non-clinical data suggest BXQ-350 improves symptoms associated with CIPN.
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